Evista increases bone density. Evista can also be used to decrease the risk of developing invasive breast cancer. Hot flashes are common during the first 6 months after starting treatment.
Evista is a prescription medicine used to treat or prevent osteoporosis in postmenopausal women. It is also used to reduce the risk of invasive breast cancer in postmenopausal women who have osteoporosis or who are at risk of invasive breast cancer.
Evista belongs to a group of drugs called selective estrogen receptor modulators (SERMs). It works by mimicking the effects of estrogen to increase the density of bone.
This medication comes in tablet form. It is taken once a day with or without food.
Common side effects include hot flashes, leg cramps, swelling, and flu-like symptoms.
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Uses of Evista
Evista is a prescription medicine used in postmenopausal women:
- to treat and prevent osteoporosis
- to lower your chance of getting invasive breast cancer
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Evista Drug Class
Evista is part of the drug class:
Side Effects of Evista
Serious and life-threatening side effects can occur while taking Evista. These include blood clots and dying from stroke:
- Increased risk of blood clots in the legs (deep vein thrombosis) and lungs (pulmonary embolism) have been reported with Evista. Women who have or have had blood clots in the legs, lungs, or eyes should not take Evista.
- Women who have had a heart attack or are at risk for a heart attack may have an increased risk of dying from stroke when taking Evista.
The most common side effects of Evista are:
- hot flashes
- leg cramps
- swelling of the feet, ankles, and legs
- flu-like syndrome
- joint pain
- sweating (hot flashes are common during the first 6 months after starting treatment)
These are not all the possible side effects of Evista. Tell your doctor about any side effect that is bothersome or that does not go away.
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- warfarin (Coumadin, Jantoven)
This is not a complete list of Evista drug interactions. Ask your doctor or pharmacist for more information.
Do not take Evista if you:
- have had blood clots in your legs, lungs or eyes.
- are pregnant, or may become pregnant, as Evista can cause harm to your baby.
- are breastfeeding
- need to lay down, be seated, or remain still for a long time (such as during long trips or being in bed after surgery) can increase the risk of blood clots. Evista may add to this risk.
- If you will need to be still for a long time, talk with your doctor about ways to reduce the risk of blood clots. On long trips, move around periodically. Stop taking Evista at least 3 days before a planned surgery or before you plan on being still for a long time. You should start taking Evista again when you return to your normal activities.
- Do not use Evista to prevent heart disease, heart attack, or strokes.
- To get the calcium and vitamin D you need, your doctor may advise you to change your diet and/or take supplemental calcium and vitamin D. Your doctor may suggest other ways to help treat or prevent osteoporosis, in addition to taking Evista and getting the calcium and vitamin D you need. These may include regular exercise, stopping smoking, and drinking less alcohol.
- Women who have hot flashes can take Evista. Evista does not treat hot flashes, and it may cause hot flashes in some women.
- Evista has not been found to cause breast tenderness or enlargement. If you notice any changes in your breasts, call your doctor to find out the cause. Before starting and while taking Evista you should have breast exams and mammograms, as directed by your doctor.
- Because Evista does not eliminate the chance of developing breast cancers, you need these examinations to find any breast cancers as early as possible.
- Evista should not cause spotting or menstrual-type bleeding. If you have any vaginal bleeding, call your doctor to find out the cause. Evista has not been found to increase the risk for cancer of the lining of the uterus.
- Women in clinical trials have taken Evista for up to eight years.
Evista Food Interactions
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Evista there are no specific foods that you must exclude from your diet when receiving Evista.
Tell your doctor about all your medical conditions including:
- If you have had blood clots in your legs, lungs or eyes.
- If you have had a stroke, mini-stroke, irregular heartbeat, high blood pressure, heart attack, history of smoking, or think you have other risk factors for stroke or heart attack.
- Raloxifene should not be used in the prevention of heart disease.
- If you are premenopausal. Only take Evista if you are past menopause.
- If you have liver or kidney disease. Women with liver or kidney disease should use Evista with caution.
- Raloxifene should not be taken with estrogens in the form of pills, patches or injections.
- If you have taken estrogen in the past and had a high increase of triglycerides (a kind of fat in the blood).
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Evista and Pregnancy
Tell your doctor if you are pregnant or planning to become pregnant. Evista should not be used in women who are or could become pregnant. Evista could harm your unborn baby.
Evista and Lactation
Tell your doctor if you are breastfeeding or planning to breastfeed. It is not known if Evista is excreted in human breast milk or if it will harm your nursing baby.
- Take Evista exactly as your doctor prescribes it.
- Keep taking Evista for as long as your doctor prescribes it for you.
- Take one Evista tablet each day, at any time of the day, with or without food.
- It is best to take Evista about the same time each day.
- If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take two doses at the same time.
Take Evista exactly as your doctor prescribes it. Follow the directions on your prescription label carefully. Your doctor will determine the best dose for you.
The recommended dose is one 60 mg Evista tablet daily, with or without food.
If you take too much Evista, call your doctor or local Poison Control Center right away.
- Store Evista at controlled room temperature at 68°F to 77°F (20°C-25°C).
- Keep Evista and all medicines out of the reach of children.
Evista FDA Warning
- Increased risk of deep vein thrombosis and pulmonary embolism have been reported with Evista. Women with active or past history of venous thromboembolism should not take Evista.
- Increased risk of death due to stroke occurred in a trial in postmenopausal women with documented coronary heart disease or at increased risk for major coronary events. Consider risk-benefit balance in women at risk for stroke.